RN1, a new polymorphicmarker near the fragile Xlocus. (HGM10 assignmentDXS 369)

Npgrj_nmeth_873 369..375

Sensory stimuli trigger complex patterns of neuronal action potentials in the brain. Measurement of these patterns is important for understanding the way the brain processes information. There are currently no efficient techniques to visualize patterns of highfrequency action potentials. Because individual action potentials result in transient increases in intracellular Ca2+, fluorescent calciu...

A New Near Optimal High Gain Controller For The Non-Minimum Phase Affine Nonlinear Systems

In this paper, a new analytical method to find a near-optimal high gain controller for the non-minimum phase affine nonlinear systems is introduced. This controller is derived based on the closed form solution of the Hamilton-Jacobi-Bellman (HJB) equation associated with the cheap control problem. This methodology employs an algebraic equation with parametric coefficients for the systems with s...

Dmd055491 369..376

Cynomolgus monkeys are a commonly used species in preclinical drug discovery, and have high genetic similarity to humans, especially for the drug-metabolizing cytochrome P450s. However, species differences are frequently observed in the metabolism of drugs between cynomolgus monkeys and humans, and delineating these differences requires expressed CYPs. Toward this end, cynomolgus monkey CYP3A4 ...

Implementing the New Deal for Fragile States

New developments in the fragile X syndrome.